Undulating historic streets lead to the palazzo of Six Senses Rome, a green sanctuary positioned at the very heart of the city on Via del Corso, just steps from the Pantheon and Trevi Fountain. In collaboration with renowned architect Patricia Urquiola, the design masterfully restores a UNESCO-listed façade and monumental staircase to their original splendor, creating an environment where Rome's timeless heritage seamlessly integrates with contemporary sustainability. Guests can retreat to one of the 96 guest rooms and suites, designed to celebrate classic Roman elements like Cocciopesto plaster and local Travertine stone. For a truly elevated experience, the two-bedroom Mellini and Lata Suites offer private kitchenettes, ideal for intimate dinners and exclusive cooking classes.

Wellness at the hotel serves as a modern tribute to heritage, anchored by the Six Senses Spa. The facility beautifully fuses the ancient art of Roman bathing—featuring a tepidarium, caldarium, and frigidarium—with high-tech biohacking therapies and customized treatments. This holistic journey is complemented by the "Sleep With Six Senses" standard, which utilizes natural hand-made mattresses and organic cotton sheets to ensure a restorative night's rest after a day of discovery.

The culinary soul of the property emphasizes a plant-based, planet-friendly philosophy with a nod to Roman traditions. Guests can begin their day with a healthy breakfast at BIVIUM Restaurant-Café-Bar, a vibrant space where local community mingles with international travelers, or ascend to the NOTOS Rooftop for creative sips and bites surrounded by panoramic views of the city's monuments. Every detail, from the interactive Earth Lab to the custom watercolor masterclasses using Italian artisanal paints, is designed to take guests on an authentic journey of reconnection and mindful rejuvenation in the Italian capital.